Describe a particular challenge or aspect of the conduct of a systematic review and present either their way of dealing with this or the approach that they would take to deal with it.

Describe a particular challenge or aspect of the conduct of a systematic review and present either their way of dealing with this or the approach that they would take to deal with it.The assignment has to be 1500 each separate two assignments that means excluding reference and introduction and graphs Eligibility (selection) criteria • Remember: you’re not designing a new study, you have to cope with what others did in the past in other places in their studies. • Considering the participants you want to include in your review, would a few that you don’t want ‘contaminate’ the entire study? • If you include a list of interventions, is this a closed list or some examples (e.g. the beta-blockers or the types of botox)? • Eligibility criteria don’t have to match your question perfectly. Can you borrow from other areas (such as melanoma thickness greater than 0.75mm)? Reasons for searching • To be comprehensive (find everything) – Get the correct answer – Avoid missing something important – Avoid missing anything – Have the complete collection (‘stamp collector’) – Maximise precision and power – Minimise bias – Widen and improve applicability or generalisability – Explore heterogeneity – Reassure yourself and the reader Learning objectives to understand publication bias to decide where to look for studies relevant to your review to understand the relative merits of different sources of studies to experience the use of trial registers as a source of studies for reviews to decide how to determine if a study meets the eligibility criteria for your review you use up a lot of the word limit in the introductory part, and it would be better to shorten that and to write more about additional searching methods, such as looking through journals or conference proceedings. checking the reference lists of articles you find and searching for unpublished or ongoing studies in trial registries.