Describe viral entry (internalization),transport via early endosomes to the ER-Golgi for replication, synthesis and packaging,and lastly, transport via late endosomes back to the plasma membrane for exocytosis ofnew viruses.

Focus your attention only on the role of the cytoskeleton in the threemain parts of the SARS-CoV-2 virus (covid19) life cycle: viral entry (internalization),transport via early endosomes to the ER-Golgi for replication, synthesis and packaging,and lastly, transport via late endosomes back to the plasma membrane for exocytosis ofnew viruses. For each of these phases, explain which cytoskeletal components aremost likely involved, that is, choose microtubules or microfilaments as the majorpolymer (or “railroad tracks”) the virus uses, and which motor protein (dynein, kinesinand myosin) would be involved. You need to describe specific experiments you will useto confirm your hypothesis. In the experiments you design, be sure to indicate whichdrug(s) you will use, how you will fluorescently label the molecule you want to follow,and the kind of microscopy (confocal epifluorescence or electron microscopy) you willuse.