Do people really make any genuine choices, or are their behaviors dictated by their physical natures combined with the environmental circumstances

Do people really make any genuine choices, or are their behaviors dictated by their physical natures combined with the environmental circumstances? After all, don’t things like brain tumors, depression, social conditioning, trauma, etc. cause our behaviors to be different? In other words, don’t those things dictate our behavior? Be sure to discuss whatever evidence you have for your view.