How can a top management team lower the chances that key managers will pursue their own self-interests at the expense of stockholders?

 How can a top management team lower the chances that key managers will pursue their own self-interests at the expense of stockholders? At the expense of the employees? At the expense of other key stakeholders? Without compromising the identity of an individual or group of individuals, share examples you have witnessed where this type of behavior occurred. What action did senior management take to curb the behavior? If no action was taken, in your opinion what could have senior management done?